Metamorphosing Xenopus: A Model System for Studying the Functional Dynamics of Interacting Neural Circuits During Development
Frog metamorphosis constitutes one of the most dramatic developmental transformations in biology, involving the transition from a fish-like tadpole to a quadrupedal adult. The recent research of John Simmers has explored the developmental plasticity of spinal locomotor networks as the animal switches from larval tail-based swimming to adult limb-based propulsion. He will also speak about the adaptive neural processes that enable the animal to maintain visual acuity throughout metamorphosis as one locomotor system emerges and replaces the other.
John Simmers is Professor for Neurobiology at Université Bordeaux and currently Visiting Fellow at CAS.